IV Fentanyl to PO Oxycodone Conversion

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mg
%
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Conversion Logic
Calculation based on standard equivalence tables.

Calculated Target Dose

-- mg
25% Reduction Applied

Clinical Pearls

  • Cross-Tolerance: Incomplete cross-tolerance is common when switching opioids. A reduction of 25-50% is generally recommended for the new agent, unless pain is uncontrolled.
  • Methadone: Conversion to methadone is complex and non-linear. Higher morphine-equivalent doses require smaller conversion ratios. This calculator uses conservative estimates; refer to specific methadone protocols.
  • Fentanyl: IV Fentanyl doses are typically measured in micrograms (mcg). This calculator automatically adjusts units to mcg for Fentanyl to prevent calculation errors.
  • Patient Specifics: Always adjust for age, renal/hepatic function, and frailty. "Start low and go slow."

References

  1. CDC Clinical Practice Guideline for Prescribing Opioids for Pain. MMWR Recomm Rep 2022;71(No. RR-3):1–95.
  2. McPherson ML. Demystifying Opioid Conversion Calculations: A Guide for Effective Dosing. 2nd ed. Bethesda, MD: ASHP; 2018.
  3. CMS. Opioid Oral Morphine Milligram Equivalent (MME) Conversion Factors. 2023.
  4. Treisman GJ, Clark MR. A Guide to Chronic Pain Assessment and Management. Johns Hopkins University Press; 2011.

Common Conversions

Quick links to standard equianalgesic calculations.

PO Hydrocodone To PO Oxycodone PO Oxycodone To PO Morphine IV Morphine To PO Morphine IV Hydromorphone To IV Morphine PO Hydromorphone To IV Hydromorphone IV Fentanyl To IV Morphine IV Fentanyl To PO Oxycodone PO Tramadol To PO Hydrocodone PO Codeine To PO Hydrocodone PO Morphine To PO Hydromorphone PO Oxycodone To IV Hydromorphone PO Oxycodone To PO Morphine